NYC Biotech & Healthtech Startups Hiring in 2026 — 30 Fast-Growing Companies

New York City has quietly become one of the most important life sciences hubs in the world — and 2026 is shaping up to be a breakout year. NYC healthtech companies raised over $4 billion in 2024 alone, a 60% jump from the year prior, and early 2026 funding data suggests that pace hasn't slowed. From AI-powered drug discovery to maternal care platforms and mental health tech, the city's biotech and healthtech ecosystem is expanding fast — and hiring faster.

Whether you're a software engineer, clinical researcher, data scientist, or go-to-market professional, there has never been a better time to look at NYC's life sciences startups. Below are 30 venture-backed companies actively hiring this February, or that just raised significant funding and are almost certainly building out their teams in the coming weeks.

🧬 AI-Powered Drug Discovery & Biotech Platforms

1. Formation Bio

Stage: Series D | Backed by: a16z, Sequoia, Tiger Global

Formation Bio is an AI-native pharma company with a genuinely different model — they acquire clinical-stage drugs from big pharma and use their proprietary technology platform to develop them faster and at lower cost. With a deep bench of ML and clinical talent, they're one of the most technically sophisticated biotech startups in NYC. They're actively hiring across data science, clinical operations, and engineering.

2. Schrödinger

Stage: Public (SDGR) / Venture-backed origins | Backed by: Bill Gates, D.E. Shaw, Wellcome Trust

NYC-headquartered Schrödinger builds computational chemistry software used by virtually every major pharma company on earth to accelerate drug discovery. They're a rare NYC biotech success story that went public while keeping their HQ in Manhattan — and they're still growing. Open roles span software engineering, computational chemistry, and sales.

3. Proxima Bio

Stage: Seed | Backed by: AIX Ventures, Roivant Sciences, DCVC, NVentures (NVIDIA)

One of the most exciting early-stage NYC biotechs right now. Proxima raised a new seed round in January 2026, bringing total funding to $86.3M — an unusually large amount for a seed company, and a signal of how seriously investors are taking their programmable medicine platform. They're building medicines that modulate protein interactions to address disease, and with NVIDIA's venture arm and Roivant among their backers, expect aggressive hiring ahead. Check their careers page.

4. Output Biosciences

Stage: Seed | Backed by: YC and others (stealth-stage details limited)

Output Biosciences is pioneering what they call Biologically-Aware Generative AI — large biological models designed to understand complex biological systems and generate novel medicines. This is early-stage, high-ambition science backed by top investors. They're currently building their founding team in NYC, and if you want to work on generative AI applied to drug discovery from day one, this is worth watching.

5. Serinus Biosciences

Stage: Seed | Backed by: Y Combinator, top institutional investors

Founded by MIT PhDs and advised by scientists from the Broad Institute, Dana-Farber, and UCSD, Serinus uses AI to design cancer combination therapies that override treatment resistance. Their fully explainable AI platform is built on decades of systems biology knowledge — a meaningful differentiator in a crowded space. Early-stage and actively building the team. See open roles.

🩺 Digital Health & Virtual Care

6. Pomelo Care

Stage: Series C | Backed by: First Round Capital, a16z, Allen & Company

Pomelo just closed a Series C and is expanding beyond maternity care to serve women across their full health journey — from fertility and pregnancy to pediatrics, perimenopause, and menopause. They're one of the strongest-performing virtual care companies in the country, with documented outcomes improvements and deep payer relationships. Open roles include recruiters, clinical staff, operations, and engineers.

7. Ro

Stage: Late-stage / Series D | Backed by: General Catalyst, FirstMark Capital, TQ Ventures

Ro is one of New York's most valuable health companies, building a vertically integrated digital healthcare platform covering men's health, women's health, weight management, and more. With its own pharmacy, lab network, and primary care infrastructure, Ro is building something genuinely different from most telehealth companies. They're actively hiring across clinical, product, and engineering.

8. Grow Therapy

Stage: Series C | Backed by: TCV, Sequoia, SignalFire

Grow Therapy is rebuilding the plumbing behind mental healthcare — making it dramatically easier for therapists to launch private practices that take insurance, while expanding patient access. They're one of the fastest-growing healthtech companies in NYC and hiring aggressively across engineering, operations, and growth.

9. Ophelia

Stage: Series B | Backed by: Y Combinator, Refactor Capital, Torch Capital

Ophelia replaces traditional rehab with telemedicine for opioid addiction treatment — using medication-assisted treatment (MAT) to deliver an approach that is clinically proven to be dramatically more effective than most in-person programs. With the opioid crisis still raging, this is urgent, important work. Ophelia is currently hiring in clinical, operations, and tech roles.

10. Craniometrix

Stage: Series A | Backed by: YC, institutional investors

Craniometrix just raised a $15M Series A in early 2026 and hit $4M in ARR with their dementia care navigation platform. They use AI to support families and patients managing dementia, reducing hospitalizations and helping Medicare-covered coaching scale nationally. This is a company early in its growth curve with real revenue and a compelling mission. They're actively hiring.

11. Nitra

Stage: Series B | Backed by: Andreessen Horowitz, QED Investors

Nitra sits at the intersection of healthtech and fintech, offering financial products (cards, credit, banking) specifically designed for healthcare professionals. It's a clever wedge — healthcare workers are underserved by traditional financial products, and Nitra's data gives them an edge. They're expanding their NYC team in product and operations.

12. Cedar

Stage: Series D | Backed by: Andreessen Horowitz, Thrive Capital, Tiger Global

Cedar modernizes the patient financial experience — replacing the confusing, paper-heavy billing process at hospitals with a consumer-grade digital interface. With major health system partnerships and over $200M raised, they're one of the most mature healthtech companies on this list. Engineering, product, and customer success roles are open.

13. Fabric Health

Stage: Series B | Backed by: Thrive Capital, a16z, GV

Fabric is streamlining healthcare administration and patient intake — sitting between patients, providers, and payers to make the whole system less painful. They've raised significant capital and are actively building out engineering and product teams.

🧠 Mental Health & Behavioral Health

14. Gilgamesh Pharmaceuticals

Stage: Series B | Backed by: Y Combinator, prominent biotech investors

Gilgamesh is one of the most scientifically serious companies working in psychedelic-inspired medicine. They're a clinical-stage biotech focused on developing novel chemical entities (NCEs) — not repurposed drugs — using a disciplined combination of medicinal chemistry, neuroscience, and IP strategy. They're hiring clinical and research staff as they advance their pipeline.

15. Spring Health

Stage: Series E | Backed by: Tiger Global, Kinnevik, General Catalyst

Spring Health is the mental health benefits platform with arguably the most rigorous clinical model in the market — using precision medicine to match members to exactly the right care, faster. They've crossed $100M+ ARR and are still hiring aggressively across clinical, sales, and engineering.

16. Alma

Stage: Series D | Backed by: Insight Partners, Tusk Ventures, Primary Venture Partners

Alma helps mental health practitioners run their practices more efficiently — handling billing, scheduling, and insurance contracting — so clinicians can focus on patients. They've built one of the largest therapist networks in the country. Open roles across product, engineering, and provider success.

🔬 Clinical Trials & Research Infrastructure

17. TrialSpark

Stage: Series C | Backed by: Andreessen Horowitz, Google Ventures

TrialSpark runs end-to-end clinical trials through their own network of trial sites, making the process dramatically more efficient and patient-centric. Clinical trial infrastructure is notoriously broken, and TrialSpark is one of the most ambitious attempts to fix it. They're hiring across clinical operations, data, and engineering.

18. Inato

Stage: Series B | Backed by: Servier, Pfizer Ventures, Bpifrance

Inato connects community-based research centers to clinical trials across the globe — unlocking patient populations that traditional sites miss, and helping pharma companies run more representative trials. They're hiring in NYC across operations, sales, and engineering.

19. Benchling

Stage: Series F | Backed by: Benchmark, Andreessen Horowitz, ICONIQ Capital

Benchling builds the R&D operating system for biotech — the cloud platform where scientists manage experiments, data, and collaboration. Nearly every major biotech company in the world uses Benchling. They have a significant NYC presence and are hiring across engineering, product, customer success, and sales.

🤱 Women's Health & Fertility

20. Legacy

Stage: Series B | Backed by: FirstMark Capital, Bain Capital Ventures, Section 32

Legacy is the leading male fertility and sperm health company — offering at-home testing, sperm freezing, personalized supplements, and telehealth. Founded at Harvard and backed by celebrity investors alongside institutional VCs, they've turned a neglected corner of fertility into a real company. They're hiring in clinical, marketing, and product.

21. Celmatix

Stage: Series C | Backed by: GV, Merck Global Health Innovation Fund, Pappas Capital

Celmatix is a precision medicine company focused on women's health — using genomics and data science to improve outcomes in fertility, hormonal health, and beyond. They're one of the more established women's health biotechs in NYC. Check their open roles.

📊 Oncology & Precision Medicine

22. Flatiron Health

Stage: Growth (Roche affiliate) | Backed by: Roche, GV, Allen & Company

Flatiron Health organizes real-world oncology data and sells it to cancer centers, researchers, and pharma companies to improve patient outcomes and accelerate drug development. With over 5 million patient records and backing from Roche, Flatiron is one of the most impactful healthtech companies in the world — and still functions with startup energy. They're actively hiring across data science, engineering, and clinical science.

23. Tempus

Stage: Public (TEM) / Late-stage | Backed by: Google Ventures, T. Rowe Price, others

Tempus uses AI to advance precision medicine — combining one of the world's largest libraries of multimodal clinical and molecular data with AI tools to help doctors personalize cancer care in real time. They went public in 2024 and are still hiring aggressively. Open roles span marketing, engineering, clinical science, and more.

🏥 Health System Infrastructure & AI

24. AiCure

Stage: Series B | Backed by: National Science Foundation, Jazz Venture Partners

AiCure uses AI to understand how patients respond to treatments in clinical trials — using computer vision to verify medication adherence and generate richer behavioral data. It's a compelling niche at the intersection of pharma and AI. They're hiring in NYC across data science and clinical partnerships.

25. Massive Bio

Stage: Series B | Backed by: key healthcare investors

Massive Bio connects cancer patients to clinical trials through AI-powered matching — dramatically reducing the time patients spend searching for treatment options. They're a NYC-based company doing genuinely important work in oncology access. See their open roles.

26. Clipboard Health

Stage: Series C | Backed by: Y Combinator, Andreessen Horowitz

Clipboard Health connects healthcare workers — nurses, CNAs, and allied health professionals — with open shifts at hospitals and care facilities. They've grown into one of the largest healthcare staffing platforms in the country. They're hiring across engineering, operations, and marketplace roles.

🌱 Freshly Funded — Watch for March Hiring

27. Proxima Bio (listed above — worth repeating)

Just raised new seed funding in January 2026. With $86M+ in the bank and NVIDIA's venture arm as a backer, expect significant team expansion in Q1 2026.

28. Pomelo Care (Series C, January 2026)

Closed a fresh Series C at the start of 2026 to expand beyond maternity care. Hiring now across clinical and operations and will almost certainly add engineering and product headcount in Q1/Q2.

29. Craniometrix (Series A, late 2025/early 2026)

Hit $4M ARR and just closed a $15M Series A. With Medicare now reimbursing their dementia coaching model, they have a clear path to scale and need the team to match. Hiring now.

30. Output Biosciences (Seed, stealth — 2025/2026)

Backed by YC and operated by repeat founders and biotech veterans. Building Large Biological Models for drug discovery. This is a founding team hire situation — if you want to be one of the first 20 people at an exceptionally ambitious AI-biotech company, this is the one to watch.

How to Break Into NYC Biotech & Healthtech in 2026

NYC's biotech and healthtech scene skews heavily toward software-enabled models — companies that use data, AI, and technology to solve healthcare problems, rather than pure lab science. That means the talent pool needed is unusually broad.

For software engineers: Companies like Formation Bio, Flatiron Health, Cedar, and Grow Therapy are hiring across the full stack. Experience in healthcare data (HL7, FHIR, EHR integrations) is increasingly valuable but not always required.

For clinical and scientific roles: Schrödinger, Proxima Bio, Formation Bio, TrialSpark, and Inato all hire research scientists, clinical operations managers, and regulatory affairs specialists at various levels.

For business and GTM roles: Most of these companies have real commercial operations and need sales, customer success, partnerships, and marketing talent. Spring Health, Alma, Cedar, and Tempus are among the most active on this front.

For data scientists and ML engineers: This is the single most in-demand profile across the NYC healthtech ecosystem right now. Output Biosciences, Serinus, Proxima, and Formation Bio are all building at the frontier of biological AI.

The city's $500M LifeSci NYC initiative has been catalytic — building wet lab infrastructure that didn't exist five years ago and drawing researchers who previously had to go to Boston or San Francisco. The next five years in NYC biotech are going to be unlike anything we've seen before.

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